Now that version 12.2.2 of Ops Center is out, you might be interested in upgrading.
We've put together a guide that walks you through the upgrade process. Each type of environment - HA or single Enterprise Controller - has separate chapters explaining how to do the upgrade through the UI or from the command line.
Something to note is that, if you're using an embedded database, the upgrade includes an upgrade of the DB to Oracle Database 220.127.116.11. If you're using an embedded database, you'll have to log into MOS and download the new DB bundles. The doc explains this step too, but if you've done upgrades in the past it'll be new to you. If you're using a customer-managed database, 18.104.22.168 is also now officially supported.