It is possible to migrate an E-Business Suite database to a new character set. You might need to do this when you expand your EBS deployment to additional countries, or when preparing for an upgrade to an EBS release that will be used globally.
You will generally migrate your EBS character set to Unicode (AL32UTF8). You must use the Database Migration Utility for Unicode (DMU) to scan for data conversion issues.
Instructions for using the DMU tool with EBS character set conversions are published here: