Yes. All versions of Oracle E-Business Suite require Oracle Database Enterprise Edition. Oracle Database Enterprise Edition is a mandatory requirement for EBS 12.2, 12.1 and older EBS releases. This applies to all Oracle Database releases, including Database 12.1, 11.2, and older Database releases certified with EBS.
It is not possible to run Oracle E-Business Suite with other Oracle Database editions, including:
Why is Oracle Database Enterprise Edition a mandatory prerequisite for EBS today?
The Oracle E-Business Suite is designed to support a wide range of deployment architectures, from small single-office instances to highly-secure, highly-available Global Single Instance deployments. To support these architectures, the E-Business Suite uses a broad range of database features and extra cost options such as Advanced Queuing, Data Guard, Virtual Private Databases, Secure Application Roles, Fine-Grained Auditing, Advanced Security, Label Security, Materialized Views, Database Vault, Partitioning, OLAP, Advanced Compression, Connection Manager, and more.
Will Oracle Database Enterprise Edition always be a mandatory prerequisite?
It is expected that Oracle Database Enterprise Edition will be a mandatory prerequisite for all future Oracle E-Business Suite releases and Database release combinations.
The Enterprise Edition is the only Database edition that includes all of those components. Enterprise Edition is the only Database edition certified and supported for use with E-Business Suite environments
The preceding is intended to outline our general product direction. It is intended for information purposes only, and may not be incorporated into any contract. It is not a commitment to deliver any material, code, or functionality, and should not be relied upon in making purchasing decision. The development, release, and timing of any features or functionality described for Oracle’s products remains at the sole discretion of Oracle.